@article { author = {Fakhr Yasseri, Alimohammad and Taheri, Diana}, title = {Urinary Stone Management During COVID-19 Pandemic}, journal = {Translational Research in Urology}, volume = {2}, number = {1}, pages = {1-3}, year = {2020}, publisher = {Urology Research Center, Tehran University of Medical Sciences}, issn = {2717-042X}, eissn = {2717-042X}, doi = {10.22034/tru.2020.245645.1030}, abstract = {Nowadays, Coronavirus disease 2019 (COVID-19) is a major health problem worldwide. So, regarding the highly recommended homestay strategies for preventing COVID-19, the usual treatment platform for several diseases has changed. During self-quarantine, the urolithiasis treatment is completely different. However, we can suggest conservative treatment for three months during the COVID-19 outbreak, and after that, a reevaluation of the patient will be done. Thus, the operation could be chosen carefully based on the patient's and urologist’s preferences and the infection rate in that center.}, keywords = {Urinary stone,urology,COVID-19,Pandemic,urolithiasis}, url = {http://www.transresurology.com/article_114217.html}, eprint = {http://www.transresurology.com/article_114217_342cf65bc73fd8ec9cecc34201f60a58.pdf} } @article { author = {Shabaninia, Shahram and Yahyazadeh, Seyed Reza and Mousavi, Arman and Kasaeian, Amir}, title = {The Characteristics and Outcomes of Patients Treated with Percutaneous Nephrolithotomy According to the Preoperative Renal Function Levels}, journal = {Translational Research in Urology}, volume = {2}, number = {1}, pages = {4-8}, year = {2020}, publisher = {Urology Research Center, Tehran University of Medical Sciences}, issn = {2717-042X}, eissn = {2717-042X}, doi = {10.22034/tru.2020.239119.1025}, abstract = {IntroductionThe principles of nephrolithiasis therapy in patients with chronic kidney disease are the same as in patients with normal kidneys. Percutaneous nephrolithotomy (PNL) is the standard treatment for patients with complex or large-volume upper urinary tract calculi. We reported the characteristics and outcomes of patients following percutaneous nephrolithotomy according to their preoperative renal function levels.MethodsData on 53 consecutive patients treated with percutaneous nephrolithotomy in this prospective cohort study in 6 months were collected. Patients were divided into 3 groups by estimated glomerular filtration rate (eGFR) including chronic kidney disease (CKD) stages 0, 1 and 2 (eGFR ≥ 60 mL/min/1.73 m2), stage 3 (eGFR = 30 to 59 mL/min/1.73 m2) and stages 4 and 5 (eGFR < 30 mL/min/1.73 m2).Results31 patients with CKD stages 0, 1, and 2, 17 with CKD stage 3, and 5 with stages 4 and 5 were followed up for at least three months. The mean eGFR before and after PNL was 80.1 vs. 85.9, 47.6 vs. 49.1, and 23.5 vs. 23.4 mL/min/1.73 m2 in the mild, moderate, and severe CKD groups, respectively. Based on the statistical analysis, eGFR in the mild group had significantly increased compared to the other groups, whereas there was no considerable difference between the moderate and severe groups.ConclusionsBy the removal of kidney stones, the progression of CKD may be halted. While significant improvement was observed in early-stage CKD, sometimes unexpected deterioration could occur in patients at the end stages of renal disease.}, keywords = {Nephrolithiasis,Renal Insufficiency,Chronic,nephrolithotomy,Percutaneous}, url = {http://www.transresurology.com/article_114223.html}, eprint = {http://www.transresurology.com/article_114223_0fbcfc4b87d1e27b7de15fabaaff1c75.pdf} } @article { author = {Khatami, Fatemeh and Guitynavard, Fateme}, title = {Cornus Mas and Urinary Tract Infections Treatment}, journal = {Translational Research in Urology}, volume = {2}, number = {1}, pages = {9-11}, year = {2020}, publisher = {Urology Research Center, Tehran University of Medical Sciences}, issn = {2717-042X}, eissn = {2717-042X}, doi = {10.22034/tru.2020.245624.1028}, abstract = {Urinary tract infections (UTIs) are complicated to treat, and patients frequently will have the problem of infection recurrence after a complete cure. Usually, UTI treatment is done by antibiotics, but the problem of bacterium resistance and sensitivity should always be kept in mind. The recent trends in herbal medicine open new insight into cranberry (Cornus mas) as a promising anti-infection and anti-cancer substance. It has shown anti-infection properties in UTIs, especially for thoroughly treating recurrent urinary tract infections. However, it can increase the risk of kidney stones and interaction with warfarin.  }, keywords = {Urinary tract infections,Herbal medicine,Cornus Mas}, url = {http://www.transresurology.com/article_117640.html}, eprint = {http://www.transresurology.com/article_117640_8f88331a907dd37c9d6e4c8e17d69ce0.pdf} } @article { author = {Guitynavard, Fateme and Tamehri Zadeh, Seyed Saeed and Naghdipoor Farhadabad, Mehdi and Gholamnejad, Maryam and Rakebi, Mohammad Mehdi and Aghamir, Seyed Mohammad Kazem}, title = {A Case Report of Electric Wire as Foreign Body in Urinary Bladder}, journal = {Translational Research in Urology}, volume = {2}, number = {1}, pages = {12-16}, year = {2020}, publisher = {Urology Research Center, Tehran University of Medical Sciences}, issn = {2717-042X}, eissn = {2717-042X}, doi = {10.22034/tru.2020.246031.1032}, abstract = {IntroductionThere are reports that various foreign bodies were inserted into urogenital tracts, and urologists have been facing this issue for many years. Foreign bodies in the bladder may be attributed to self-infliction, iatrogenic issues, or migration from other adjacent organs. In children, curiosity and playfulness may be the primary motives for inserting objects into the urethra.Case Presentations Here, a case report of a 19-year-old boy who inserted a wire (telephone cable) into his bladder is presented. Under general anesthesia, the cystoscopy was performed and using grasper the cable was removed from the bladder of the patient. He was discharged a day after with just a few irritative symptoms. At the time of discharge, the patient’s parents were advised for psychiatric consultation.ConclusionsThe foreign body of the bladder in patients can happen in a patient with a mental health disorder. To diagnose through pelvic radiograph plays a crucial role in the diagnosis of the disease.}, keywords = {Bladder,Foreign body,lower urinary tract symptoms}, url = {http://www.transresurology.com/article_117643.html}, eprint = {http://www.transresurology.com/article_117643_2b3264eb9c0ead7ce570d0b70755e541.pdf} } @article { author = {Mashhadi, Rahil and Khatami, Fatemeh and Zareian Baghdadabad, Leyla and Shabestari, Alireza Namazi and Guitynavard, Fateme and Oliveira Reis, Leonardo}, title = {A Review of Animal Laboratory Practice in the COVID-19 and Safety Concerns}, journal = {Translational Research in Urology}, volume = {2}, number = {1}, pages = {17-21}, year = {2020}, publisher = {Urology Research Center, Tehran University of Medical Sciences}, issn = {2717-042X}, eissn = {2717-042X}, doi = {10.22034/tru.2020.249149.1033}, abstract = {The research in biomedical sciences is based on primary research on animals. Due to the coronavirus disease-2019 (COVID-19) pandemic, many research projects involving animal studies have faced interruptions due to the raised concerns about the safety of working with animals The disruption in such research projects has raised significant concerns in biomedical scientific research worldwide. Assessing and evaluating the safety and feasibility of research projects on animal models seems necessary. This study provides evidence of the feasibility of continuing research activities in animal laboratories during the COVID-19 pandemic. According to the results of studies, the risk of COVID-19 is low in routine laboratory animals, including mice, rats, and pigs.By examining the available data from our animal laboratory and continuing research activities on low-risk animals, with adequate safety and personal protective equipment available at the facility, animal studies could be carried forward without endangering the safety of the researcher and society.}, keywords = {Coronavirus,Animal laboratory,Biomedical Research,COVID-19}, url = {http://www.transresurology.com/article_118063.html}, eprint = {http://www.transresurology.com/article_118063_aae6a1c382745657b5ac97c16b86acc2.pdf} } @article { author = {Ghasemlouei, Amir and Khayyamfar, Feraidoon and Foroutan, Seyed Kazem and Rajabi, Mostafa}, title = {Effect of Modified Vacuum in Patients with Peyronie’s Disease and Erectile Dysfunction}, journal = {Translational Research in Urology}, volume = {2}, number = {1}, pages = {22-27}, year = {2020}, publisher = {Urology Research Center, Tehran University of Medical Sciences}, issn = {2717-042X}, eissn = {2717-042X}, doi = {10.22034/tru.2020.237420.1024}, abstract = {IntroductionPeyronie's disease (PD) is a penile disease that is characterized by penile pain, curvature, shortening, and plaque in the penis, which usually ends up in erectile dysfunction (ED). This study assesses the efficacy of modified vacuum therapy in patients with PD and ED. The basic principle of the study is similar to modeling performed during penile implant surgery. MethodsThis study was performed on 43 Patients who practiced with three different vacuum cylinders for 30 minutes, 3 times a day for 3 months. First, the second and third months with the smallest, medium, and biggest cylinders were used, respectively. Parameters were recorded before the beginning of the study at the end of each month. Assessment includes the number and size of the plaque, angle of penile curvature (by erection induced with vacuum constriction device (VCD)), pain during erection, the status of morning erection, quality of an erection, and various previous treatments. There was a clinically and statistically significant improvement in the angle of curvature, size, and number of plaques.  ResultsA total of 43 patients with a mean age of 56.3 years(40-74) participated in the study. There was a significant reduction in plaque size and curvature. The mean of plaque size and curvature was 1.39cm and 31.28 degrees, respectively, at the presentation, which was reduced to 0.64 (0-3)cm and 11.6 degrees, respectively, at the study's end. At the end of the study, 30(69.7%) patients were satisfied with the outcome and wanted no further treatment. There was no significant side effect observed in patients using the device. ConclusionsWe recommend using a modified vacuum device with the mentioned method for PD and ED with curvature less than 45 degrees and plaque size less than 2cm. It is safe to use in all stages of the disease and can help patients to attain erection with VCD.}, keywords = {Peyronie’s Disease,penile curvature,penile plaque,Erectile Dysfunction,Vacuum pump therapy}, url = {http://www.transresurology.com/article_118590.html}, eprint = {http://www.transresurology.com/article_118590_dd8d96b11e7e91e7f81afa7bf4c2f0bd.pdf} } @article { author = {Khalil, Masoud and Yousefichaijan, Parsa and Fakhr Yasseri, Alimohammad}, title = {Unusual Complication of Ewing Sarcoma of Vulva: Case Report}, journal = {Translational Research in Urology}, volume = {2}, number = {1}, pages = {28-31}, year = {2020}, publisher = {Urology Research Center, Tehran University of Medical Sciences}, issn = {2717-042X}, eissn = {2717-042X}, doi = {10.22034/tru.2020.255363.1039}, abstract = {IntroductionPrimary Ewing sarcoma of the vulva is an extremely rare tumor with less than 10 molecular confirmed reported cases. Urinary retention in this case is an unusual manifestation. Case presentationWe describe a 15 years-old female patient with advanced Ewing sarcoma of the vulva and urinary retention during chemotherapy. The technique of catheterization with two catheters could be interesting, in this case as well. When it comes to Immunohistochemistry, tumor cells displayed CD99, NIKX2. ConclusionsIn all cells and proliferative capacity of KI-67 in 40% of tumor cells, but other markers were negative.}, keywords = {Sarcoma,Ewing,Vulva Neoplasms,Vulva,Urinary retention}, url = {http://www.transresurology.com/article_118963.html}, eprint = {http://www.transresurology.com/article_118963_d0a838d39bba4b7fb26e4696e968843e.pdf} }