TY - JOUR ID - 118590 TI - Effect of Modified Vacuum in Patients with Peyronie’s Disease and Erectile Dysfunction JO - Translational Research in Urology JA - TRU LA - en SN - AU - Ghasemlouei, Amir AU - Khayyamfar, Feraidoon AU - Foroutan, Seyed Kazem AU - Rajabi, Mostafa AD - Medical Department, General Surgery Resident of Tehran University of Medical Science,Tehran,Iran AD - Urology Ward, Mostafakhomeini Hospital,Shahed University of Medical Science, Tehran, Iran AD - Medical Department,General Surgeon,Isfahan University of Medical Science,Isfahan,Iran Y1 - 2020 PY - 2020 VL - 2 IS - 1 SP - 22 EP - 27 KW - Peyronie’s Disease KW - penile curvature KW - penile plaque KW - Erectile Dysfunction KW - Vacuum pump therapy DO - 10.22034/tru.2020.237420.1024 N2 - IntroductionPeyronie's disease (PD) is a penile disease that is characterized by penile pain, curvature, shortening, and plaque in the penis, which usually ends up in erectile dysfunction (ED). This study assesses the efficacy of modified vacuum therapy in patients with PD and ED. The basic principle of the study is similar to modeling performed during penile implant surgery. MethodsThis study was performed on 43 Patients who practiced with three different vacuum cylinders for 30 minutes, 3 times a day for 3 months. First, the second and third months with the smallest, medium, and biggest cylinders were used, respectively. Parameters were recorded before the beginning of the study at the end of each month. Assessment includes the number and size of the plaque, angle of penile curvature (by erection induced with vacuum constriction device (VCD)), pain during erection, the status of morning erection, quality of an erection, and various previous treatments. There was a clinically and statistically significant improvement in the angle of curvature, size, and number of plaques.  ResultsA total of 43 patients with a mean age of 56.3 years(40-74) participated in the study. There was a significant reduction in plaque size and curvature. The mean of plaque size and curvature was 1.39cm and 31.28 degrees, respectively, at the presentation, which was reduced to 0.64 (0-3)cm and 11.6 degrees, respectively, at the study's end. At the end of the study, 30(69.7%) patients were satisfied with the outcome and wanted no further treatment. There was no significant side effect observed in patients using the device. ConclusionsWe recommend using a modified vacuum device with the mentioned method for PD and ED with curvature less than 45 degrees and plaque size less than 2cm. It is safe to use in all stages of the disease and can help patients to attain erection with VCD. UR - http://www.transresurology.com/article_118590.html L1 - http://www.transresurology.com/article_118590_dd8d96b11e7e91e7f81afa7bf4c2f0bd.pdf ER -